Percocet is a prescription painkiller used for moderate to moderately severe pain. It combines two active ingredients: oxycodone, an opioid that blocks pain signals in the brain, and acetaminophen (the same ingredient in Tylenol), which reduces pain through a different pathway. Percocet is a prescription medication used for the management of pain severe enough to require an opioid analgesic and for which alternatives are inadequate. Learn what Percocet is, how it works for pain relief, common side effects, and risks. Plus, treatment options if you're concerned about dependency. Oxycodone/paracetamol, sold under the brand name Percocet among others, [2] is a fixed-dose combination of the opioid oxycodone with paracetamol (acetaminophen), used to treat moderate to severe pain. Percocet® 2.5 mg/325 mg tablets (2.5 milligrams (mg) of oxycodone and 325 mg of acetaminophen): 1 or 2 tablets every 6 hours as needed. Your doctor may adjust your dose as needed. Percocet (Oxycodone and Acetaminophen) may treat acute and moderate-to-server pain, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and drug imprint. Find patient medical information for Oxycodone/Acetaminophen (Percocet, Tylox, and others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings What is Percocet, and what is it used for? Percocet (oxycodone/acetaminophen) is a strong narcotic pain -reliever and cough suppressant similar to morphine, codeine, and hydrocodone. Percocet is prescribed for the relief of moderate to moderately severe pain. Percocet (oxycodone / acetaminophen) is a combination opioid medication. It's used to treat pain when non-opioid medications aren't working well enough to control pain. It's a controlled substance because it has a high risk of misuse, dependency, and addiction. Percocet is a prescription painkiller combining oxycodone and acetaminophen. It's used for severe pain when other non-opioid pain treatments haven't worked or cannot be tolerated.